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常规凝血检验项目在异位妊娠大出血输血治疗效果监测及预测中的作用探讨
作者:赵丽娟 刘娟 潘枫 熊德琼 张泽君 
单位:(四川省达州市中西医结合医院输血科 达州 635000) 
关键词:异位妊娠 凝血指标 血常规 输血治疗 
分类号:R714.22;R446.11
出版年,卷(期):页码:2019,47(6):444-447
摘要:


  【摘要】 目的 探讨常规凝血检验项目在异位妊娠大出血输血治疗效果监测及预测中的作用。方法 选取2016年3月~2018年9月收治的异位妊娠大出血患者68例,依据是否发生不良反应分成两组;对照组19例为发生不良反应患者,研究组49例为未发生不良反应患者。观察对比治疗前后两组的相关凝血指标(PT、APTT、TT、FIB)和血常规指标(PLT、HCT、RBC、HGB水平)的变化情况。结果 研究组PT、APTT、TT较治疗前显著降低,FIB较治疗前显著升高(P<0.05),对照组上述相关凝血指标水平与治疗前相比显著升高(P<0.05);研究组相关血常规指标水平显著高于对照组(P<0.05)。结论 检验患者的相关凝血指标及血常规指标,可以评估异位妊娠患者在接受输血治疗过程中是否合并出现不良反应的风险。

Objective To explore the role of routine coagulation test items in monitoring and predicting the therapeutic effect of blood transfusion for massive hemorrhage of ectopic pregnancy.Methods 68 patients with massive hemorrhage of ectopic pregnancy admitted to our hospital from March 2016 to September 2018 were selected and divided into two groups according to the occurrence of adverse reactions.19 patients in control group were those with adverse reactions,and 49 patients in study group were those without adverse reactions.And then,the changes of related coagulation indexes(PT,APTT,TT and FIB) and blood routine indexes(PLT,HCT,RBC,HGB levels) were observed and compared between the two groups before and after treatment.Results The PT,APTT and TT in the study group were significantly lower than those before treatment,but the FIB was significantly higher than that before treatment(P<0.05),and the above-mentioned related coagulation indexes in the control group were significantly higher than those before treatment(P<0.05).The levels of blood routine indexes in the study group were significantly higher than those in the control group(P<0.05).Conclusion The risk of adverse reactions in patients with ectopic pregnancy during transfusion therapy can be evaluated by examining the relevant coagulation indexes and blood routine indexes of the patients.

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